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3 articles
As temperatures fall across Britain, the body mounts a coordinated hormonal response to defend its core temperature. This article traces the signalling circuitry of thermoregulation, from thyroid hormones and adrenaline to the fever response, and examines what happens when the system fails.
Britain's laboratories and museums hold a remarkable share of the discoveries that founded modern signalling science. This tour through five landmark achievements — and the places you can still visit today — traces how cAMP, kinases and more changed medicine, and where UK-funded research is heading next.
Cancer is often described as uncontrolled growth, but at the molecular level it is a failure of communication. This article traces how mutations in receptors such as EGFR and downstream proteins like RAS convert a carefully regulated dialogue into permanent, growth-driving static.